Research

We study the ordered process of myofibril breakdown by probing the functions of certain ubiquitin ligases
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Proposed model for the molecular mechanisms leading to desmin filament depolymerization durin atrophy

We investigate the mechanisms of desmin intermediate filaments depolymerization during atrophy, which we found precedes and accelerates myofibril destruction
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Proposed model for gamma-catenin role in stabilizing membrane structures and the cytoskeleton

We investigate how reduced integrity of certain membrane structures affects the stability of desmin and the bound myofibrils and causes atrophy
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